Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rab28Uncharacterized protein. (221 aa)    
Predicted Functional Partners:
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
   
 
 0.918
trim23
Tripartite motif containing 23.
   
 0.750
dennd5a
DENN/MADD domain containing 5A.
     
 0.729
spon2
Spondin 2b, extracellular matrix protein.
      
 0.721
C8orf37
Chromosome 8 open reading frame 37.
      
 0.717
dennd1b
DENN domain containing 1B.
     
 0.710
LOC106955495
Si:dkey-76b14.2.
     
 0.710
LOC106940637
DENN/MADD domain containing 1A.
     
 0.710
LOC106939615
Zinc finger protein 653.
    
 
 0.705
ENSPLAP00000004362
Uncharacterized protein.
      
 0.702
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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