Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vps33bVPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family. (613 aa)    
Predicted Functional Partners:
vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog.
   
 
 0.997
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
 0.982
vps18
VPS18 core subunit of CORVET and HOPS complexes.
   
 0.979
vps39
VPS39 subunit of HOPS complex.
   
 0.977
vps11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
   
 0.976
vps41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 0.964
tgfbrap1
Transforming growth factor, beta receptor associated protein 1.
   
 0.940
ccdc22
Coiled-coil domain containing 22.
   
 
 0.925
vps8
VPS8 subunit of CORVET complex.
    
 
 0.924
ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated.
    
 
 0.915
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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