Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hckTyrosine-protein kinase. (500 aa)    
Predicted Functional Partners:
LOC106951428
Signal transducing adaptor family member 2a.
    
 0.890
LOC106949676
Uncharacterized protein.
    
 0.876
LOC106959450
SH2 domain containing 1A duplicate b.
   
 0.862
ptpra
Receptor-type tyrosine-protein phosphatase alpha.
    
 0.807
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.792
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 0.792
LOC106960293
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.774
LOC106946273
Uncharacterized protein.
    
 0.774
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.774
ENSPLAP00000004364
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.758
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.