Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSPLAP00000004745Spartin b. (271 aa)    
Predicted Functional Partners:
ist1
IST1 factor associated with ESCRT-III.
    
 
 0.931
spart
Spartin a.
  
  
 
0.906
LOC106952138
E3 ubiquitin-protein ligase.
    
 
 0.831
ENSPLAP00000026412
Uncharacterized protein.
    
 
 0.831
ENSPLAP00000026430
HECT domain-containing protein.
    
 
 0.831
wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.809
wwp2
E3 ubiquitin-protein ligase.
    
 
 0.809
wwox
WW domain containing oxidoreductase.
    
   0.719
otulin
OTU deubiquitinase with linear linkage specificity a.
    
   0.712
tor4a
Torsin family 4, member Aa.
      
 0.680
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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