STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htra3HtrA serine peptidase 3a. (558 aa)    
Predicted Functional Partners:
LOC106936237
Sterol carrier protein 2b.
    
 0.992
scp2
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.992
katnal2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.852
ENSPLAP00000000046
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.850
psmd12
Proteasome 26S subunit, non-ATPase 12.
    
 0.828
ENSPLAP00000015767
Uncharacterized protein.
    
 0.814
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.814
pink1
PTEN induced kinase 1.
    
 0.809
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
    
 0.789
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
    
 0.789
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.