Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htra3HtrA serine peptidase 3a. (558 aa)    
Predicted Functional Partners:
LOC106964079
X-linked inhibitor of apoptosis.
    
 
 0.899
ENSPLAP00000000046
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.838
tcp1
T-complex 1.
  
 
 0.783
psmd12
Proteasome 26S subunit, non-ATPase 12.
    
 0.726
dab2
DAB adaptor protein 2.
   
    0.717
eci2
Enoyl-CoA delta isomerase 2.
   
 0.717
psmd13
Proteasome 26S subunit, non-ATPase 13.
    
 0.714
ENSPLAP00000015767
Uncharacterized protein.
    
 0.712
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 0.712
psmd8
Proteasome 26S subunit, non-ATPase 8.
   
 0.709
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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