Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
avenApoptosis, caspase activation inhibitor. (316 aa)    
Predicted Functional Partners:
LOC106940227
Uncharacterized protein.
    
 
 0.966
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.939
ENSPLAP00000020611
TROVE domain-containing protein.
    
 0.683
ENSPLAP00000020621
Uncharacterized protein.
    
 0.683
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.676
LOC106963381
Noggin; Belongs to the noggin family.
      
 0.663
ENSPLAP00000022570
Uncharacterized protein.
      
 0.659
naaladl1
Si:ch211-214j8.1.
      
 0.643
bphl
Biphenyl hydrolase like.
      
 0.623
ppp4r4
Protein phosphatase 4, regulatory subunit 4.
      
 0.623
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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