| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADK | LOC106938674 | ENSPLAP00000015947 | ENSPLAP00000008656 | Adenosine kinase. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.787 |
| ADK | LOC106947145 | ENSPLAP00000015947 | ENSPLAP00000007988 | Adenosine kinase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.787 |
| ADK | LOC106960117 | ENSPLAP00000015947 | ENSPLAP00000016966 | Adenosine kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.540 |
| ADK | adsl | ENSPLAP00000015947 | ENSPLAP00000022284 | Adenosine kinase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.970 |
| ADK | ampd1 | ENSPLAP00000015947 | ENSPLAP00000005030 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.970 |
| ADK | aprt | ENSPLAP00000015947 | ENSPLAP00000013252 | Adenosine kinase. | Adenine phosphoribosyltransferase. | 0.986 |
| ADK | atic | ENSPLAP00000015947 | ENSPLAP00000003976 | Adenosine kinase. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.810 |
| ADK | gmpr | ENSPLAP00000015947 | ENSPLAP00000015146 | Adenosine kinase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.540 |
| ADK | hprt1 | ENSPLAP00000015947 | ENSPLAP00000000161 | Adenosine kinase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.532 |
| ADK | impdh1 | ENSPLAP00000015947 | ENSPLAP00000027484 | Adenosine kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.540 |
| LOC106938674 | ADK | ENSPLAP00000008656 | ENSPLAP00000015947 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenosine kinase. | 0.787 |
| LOC106938674 | LOC106947145 | ENSPLAP00000008656 | ENSPLAP00000007988 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.954 |
| LOC106938674 | LOC106960117 | ENSPLAP00000008656 | ENSPLAP00000016966 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.983 |
| LOC106938674 | adsl | ENSPLAP00000008656 | ENSPLAP00000022284 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.997 |
| LOC106938674 | ampd1 | ENSPLAP00000008656 | ENSPLAP00000005030 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.967 |
| LOC106938674 | aprt | ENSPLAP00000008656 | ENSPLAP00000013252 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenine phosphoribosyltransferase. | 0.699 |
| LOC106938674 | atic | ENSPLAP00000008656 | ENSPLAP00000003976 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.989 |
| LOC106938674 | gmpr | ENSPLAP00000008656 | ENSPLAP00000015146 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.983 |
| LOC106938674 | hprt1 | ENSPLAP00000008656 | ENSPLAP00000000161 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.969 |
| LOC106938674 | impdh1 | ENSPLAP00000008656 | ENSPLAP00000027484 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.983 |