STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nedd4lE3 ubiquitin-protein ligase. (945 aa)    
Predicted Functional Partners:
LOC106956234
Tyrosine-protein kinase receptor.
   
 0.929
fgfr3
Fibroblast growth factor receptor.
    
 0.927
LOC106957871
Fibroblast growth factor receptor 2.
    
 0.927
egfr
Receptor protein-tyrosine kinase.
    
 0.925
rps27a
Ribosomal protein S27a.
    
 0.923
LOC106949861
Tyrosine-protein kinase receptor.
   
 0.920
LOC106934486
Receptor protein-tyrosine kinase.
    
 0.918
LOC106964182
Fibroblast growth factor receptor.
    
 0.903
ENSPLAP00000028387
Uncharacterized protein.
    
 0.897
pdgfra
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
 0.897
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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