STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106957108Folate gamma-glutamyl hydrolase. (319 aa)    
Predicted Functional Partners:
ENSPLAP00000018920
DHFR domain-containing protein.
     
 0.948
fpgs
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
     
 0.940
LOC106944947
Folate gamma-glutamyl hydrolase.
  
  
 
0.938
LOC106962160
Zgc:153031.
     
 0.937
LOC106935993
Folate gamma-glutamyl hydrolase.
  
  
 
0.923
tyms
Thymidylate synthetase.
   
 
 0.754
pold1
DNA polymerase.
     
 0.615
LOC106962054
UEV domain-containing protein.
      
 0.593
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
  
 0.535
gstz1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
     
 0.528
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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