STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (364 aa)    
Predicted Functional Partners:
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
 0.999
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.998
dld
Dihydrolipoamide dehydrogenase.
  
 
 0.995
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.991
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.991
DLST
Dihydrolipoamide S-succinyltransferase.
 
 0.990
dlst
Dihydrolipoamide S-succinyltransferase.
  
 0.988
LOC106962423
Branched chain amino-acid transaminase 2, mitochondrial.
  
 
 0.978
TXNRD2
Thioredoxin reductase 2.
  
 
 0.966
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.