nkx2-3 protein (Poecilia latipinna) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

nkx2-3

NK2 homeobox 3. (353 aa)

Predicted Functional Partners:

poll

0.508

gata5

0.452

LOC106964935

0.452

gata4

0.452

gata6

0.452

LOC106958419

0.426

LOC106953245

0.426

trps1

0.426

zglp1

0.426

gata3

0.426

Your Current Organism:

Poecilia latipinna

NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC106953245	LOC106964935	ENSPLAP00000001729	ENSPLAP00000015713	GATA binding protein 2a.	GATA binding protein 1a.	0.637
LOC106953245	gata4	ENSPLAP00000001729	ENSPLAP00000016000	GATA binding protein 2a.	GATA binding protein 4.	0.552
LOC106953245	gata5	ENSPLAP00000001729	ENSPLAP00000014183	GATA binding protein 2a.	GATA binding protein 5.	0.552
LOC106953245	gata6	ENSPLAP00000001729	ENSPLAP00000016013	GATA binding protein 2a.	GATA binding protein 6.	0.552
LOC106953245	nkx2-3	ENSPLAP00000001729	ENSPLAP00000005660	GATA binding protein 2a.	NK2 homeobox 3.	0.426
LOC106953245	trps1	ENSPLAP00000001729	ENSPLAP00000010497	GATA binding protein 2a.	Trichorhinophalangeal syndrome I.	0.462
LOC106958419	LOC106964935	ENSPLAP00000000270	ENSPLAP00000015713	Uncharacterized protein.	GATA binding protein 1a.	0.636
LOC106958419	gata4	ENSPLAP00000000270	ENSPLAP00000016000	Uncharacterized protein.	GATA binding protein 4.	0.552
LOC106958419	gata5	ENSPLAP00000000270	ENSPLAP00000014183	Uncharacterized protein.	GATA binding protein 5.	0.552
LOC106958419	gata6	ENSPLAP00000000270	ENSPLAP00000016013	Uncharacterized protein.	GATA binding protein 6.	0.552
LOC106958419	nkx2-3	ENSPLAP00000000270	ENSPLAP00000005660	Uncharacterized protein.	NK2 homeobox 3.	0.426
LOC106958419	trps1	ENSPLAP00000000270	ENSPLAP00000010497	Uncharacterized protein.	Trichorhinophalangeal syndrome I.	0.462
LOC106964935	LOC106953245	ENSPLAP00000015713	ENSPLAP00000001729	GATA binding protein 1a.	GATA binding protein 2a.	0.637
LOC106964935	LOC106958419	ENSPLAP00000015713	ENSPLAP00000000270	GATA binding protein 1a.	Uncharacterized protein.	0.636
LOC106964935	gata3	ENSPLAP00000015713	ENSPLAP00000031019	GATA binding protein 1a.	GATA binding protein 3.	0.630
LOC106964935	nkx2-3	ENSPLAP00000015713	ENSPLAP00000005660	GATA binding protein 1a.	NK2 homeobox 3.	0.452
LOC106964935	trps1	ENSPLAP00000015713	ENSPLAP00000010497	GATA binding protein 1a.	Trichorhinophalangeal syndrome I.	0.546
gata3	LOC106964935	ENSPLAP00000031019	ENSPLAP00000015713	GATA binding protein 3.	GATA binding protein 1a.	0.630
gata3	gata4	ENSPLAP00000031019	ENSPLAP00000016000	GATA binding protein 3.	GATA binding protein 4.	0.552
gata3	gata5	ENSPLAP00000031019	ENSPLAP00000014183	GATA binding protein 3.	GATA binding protein 5.	0.552