Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000006409Uncharacterized protein. (482 aa)    
Predicted Functional Partners:
huwe1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 
 0.745
ENSPLAP00000014192
NDK domain-containing protein.
    
 0.577
mysm1
Myb-like, SWIRM and MPN domains 1.
    
  0.550
LOC106961061
MYCN proto-oncogene, bHLH transcription factor.
    
 0.526
topbp1
DNA topoisomerase II binding protein 1.
    
 
 0.511
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.498
iqce
Uncharacterized protein.
    
 
 0.498
fbxl17
F-box and leucine-rich repeat protein 17.
    
   0.490
ENSPLAP00000030323
Basic leucine zipper transcription factor, ATF-like 3.
    
 0.480
ENSPLAP00000013662
E1A binding protein p300 b.
    
  0.451
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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