STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Rho guanine nucleotide exchange factor 4. (629 aa)    
Predicted Functional Partners:
apc2
APC regulator of WNT signaling pathway 2.
   
 0.960
LOC106953407
Rac family small GTPase 2.
    
 0.955
LOC106961773
Uncharacterized protein.
    
 0.951
RAC1
Rac family small GTPase 1.
    
 0.948
LOC106961755
Uncharacterized protein.
    
 0.948
LOC106961760
Uncharacterized protein.
    
 0.940
LOC106963483
Spermatogenesis associated 13.
  
  
 
0.905
ENSPLAP00000008549
APC_N_CC domain-containing protein.
   
 0.844
CDC42
Cell division cycle 42.
    
 0.794
LOC106964683
Cell division cycle 42.
    
 0.794
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.