Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
maddMAP-kinase activating death domain. (1565 aa)    
Predicted Functional Partners:
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.848
LOC106940637
DENN/MADD domain containing 1A.
    
 
 0.787
dennd5a
DENN/MADD domain containing 5A.
    
 
 0.776
RAB27B
RAB27B, member RAS oncogene family.
     
 0.771
LOC106952996
Uncharacterized protein.
     
 0.771
rab27a
RAB27A, member RAS oncogene family.
     
 0.771
syt6
Synaptotagmin VIa.
    
   0.729
LOC106955409
Synaptotagmin X.
    
   0.729
syt3
Synaptotagmin III.
    
   0.729
rab3gap1
RAB3 GTPase activating protein subunit 1.
   
  
 0.705
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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