Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000006595Ski_Sno domain-containing protein. (148 aa)    
Predicted Functional Partners:
LOC106963770
Dachshund d.
 
      0.896
tm7sf3
Transmembrane 7 superfamily member 3.
      
 0.642
eya4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.635
EYA4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.635
LOC106952136
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.635
LOC106958983
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.635
LOC106935478
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.635
med15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.524
rab28
Uncharacterized protein.
      
 0.516
setbp1
SET binding protein 1.
      
 0.509
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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