STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
lonp1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (930 aa)    
Predicted Functional Partners:
grpel1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.928
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.923
clpp
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.867
clpx
Caseinolytic mitochondrial matrix peptidase chaperone subunit b.
  
 
 0.820
hspd1
Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family.
  
 0.758
pex5l
Peroxisomal biogenesis factor 5-like a.
   
 0.750
pex5
Peroxisomal biogenesis factor 5.
   
 0.750
LOC106938693
Peroxisomal biogenesis factor 5-like b.
   
 0.750
LOC106950570-2
Heat shock 10 protein 1; Belongs to the GroES chaperonin family.
  
  
 0.745
ncdn
Neurochondrin.
     
 0.702
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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