STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brafB-Raf proto-oncogene, serine/threonine kinase. (753 aa)    
Predicted Functional Partners:
KRAS
KRAS proto-oncogene, GTPase.
  
 0.982
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.981
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.981
hras
HRas proto-oncogene, GTPase a.
  
 0.978
LOC106951627
Zgc:55558.
  
 0.977
LOC106952760
RAP1A, member of RAS oncogene family a.
  
 0.971
rap1a
RAP1A, member of RAS oncogene family b.
  
 0.971
mras
Muscle RAS oncogene homolog.
  
 0.966
LOC106941801
Uncharacterized protein.
  
 0.961
LOC106940239
Ras-related protein Rap-1b.
  
 0.961
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.