STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000022909BACK domain-containing protein. (543 aa)    
Predicted Functional Partners:
LOC106937213
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.586
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.586
cacul1
CDK2 associated cullin domain 1; Belongs to the cullin family.
    
 0.574
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.574
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.520
ube2f
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
  0.454
ube2m
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.454
rnf7
Ring finger protein 7.
    
 0.452
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.452
klhl31
Kelch-like family member 31.
  
 
0.400
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
Server load: low (26%) [HD]