STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPLAP00000025122Uncharacterized protein. (101 aa)    
Predicted Functional Partners:
LOC106940006
GRB2 related adaptor protein 2a.
   
 0.805
grb2
Growth factor receptor-bound protein 2b.
   
 0.749
ENSPLAP00000007777
FH2 domain-containing protein.
    
 0.695
FMN1
FH2 domain-containing protein.
    
 0.695
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.607
nck1
Cytoplasmic protein.
    
 0.600
nck2
Cytoplasmic protein.
    
 0.600
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
   
  0.599
gak
Cyclin G associated kinase.
   
 0.596
mars1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 0.593
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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