STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106953382Cyclin D2, a; Belongs to the cyclin family. (296 aa)    
Predicted Functional Partners:
LOC106961113
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.986
LOC106953297
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
   
 0.980
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.980
cdkn2c
ANK_REP_REGION domain-containing protein.
    
 0.980
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.979
rb1
Retinoblastoma 1.
    
 0.976
LOC106949622
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
    
 0.974
LOC106955228
Retinoblastoma-like 2 (p130).
    
 0.971
rbl1
Retinoblastoma-like 1 (p107).
    
 0.971
LOC106941275
Cyclin-dependent kinase inhibitor 1D.
   
 0.969
Your Current Organism:
Poecilia latipinna
NCBI taxonomy Id: 48699
Other names: Mollienesia latipinna, P. latipinna, sailfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.