node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSPLAP00000004509 | ENSPLAP00000029380 | ENSPLAP00000004509 | ENSPLAP00000029380 | Kynurenine 3-monooxygenase. | Epoxide hydrolase 2, cytoplasmic. | 0.720 |
ENSPLAP00000004509 | LOC106957292 | ENSPLAP00000004509 | ENSPLAP00000031725 | Kynurenine 3-monooxygenase. | Flavin-containing monooxygenase. | 0.664 |
ENSPLAP00000004509 | LOC106965291 | ENSPLAP00000004509 | ENSPLAP00000007257 | Kynurenine 3-monooxygenase. | Uncharacterized protein. | 0.746 |
ENSPLAP00000004509 | afmid | ENSPLAP00000004509 | ENSPLAP00000000800 | Kynurenine 3-monooxygenase. | Arylformamidase. | 0.981 |
ENSPLAP00000004509 | coq3 | ENSPLAP00000004509 | ENSPLAP00000020585 | Kynurenine 3-monooxygenase. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.948 |
ENSPLAP00000004509 | coq6 | ENSPLAP00000004509 | ENSPLAP00000014407 | Kynurenine 3-monooxygenase. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.554 |
ENSPLAP00000004509 | ephx1 | ENSPLAP00000004509 | ENSPLAP00000010811 | Kynurenine 3-monooxygenase. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.604 |
ENSPLAP00000004509 | lipe | ENSPLAP00000004509 | ENSPLAP00000005850 | Kynurenine 3-monooxygenase. | Lipase, hormone-sensitive b. | 0.665 |
ENSPLAP00000004509 | metap1d | ENSPLAP00000004509 | ENSPLAP00000027023 | Kynurenine 3-monooxygenase. | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). | 0.772 |
ENSPLAP00000004509 | nceh1 | ENSPLAP00000004509 | ENSPLAP00000006629 | Kynurenine 3-monooxygenase. | Neutral cholesterol ester hydrolase 1a. | 0.746 |
ENSPLAP00000029380 | ENSPLAP00000004509 | ENSPLAP00000029380 | ENSPLAP00000004509 | Epoxide hydrolase 2, cytoplasmic. | Kynurenine 3-monooxygenase. | 0.720 |
ENSPLAP00000029380 | LOC106957292 | ENSPLAP00000029380 | ENSPLAP00000031725 | Epoxide hydrolase 2, cytoplasmic. | Flavin-containing monooxygenase. | 0.672 |
ENSPLAP00000029380 | LOC106965291 | ENSPLAP00000029380 | ENSPLAP00000007257 | Epoxide hydrolase 2, cytoplasmic. | Uncharacterized protein. | 0.584 |
ENSPLAP00000029380 | afmid | ENSPLAP00000029380 | ENSPLAP00000000800 | Epoxide hydrolase 2, cytoplasmic. | Arylformamidase. | 0.564 |
ENSPLAP00000029380 | coq3 | ENSPLAP00000029380 | ENSPLAP00000020585 | Epoxide hydrolase 2, cytoplasmic. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.849 |
ENSPLAP00000029380 | coq6 | ENSPLAP00000029380 | ENSPLAP00000014407 | Epoxide hydrolase 2, cytoplasmic. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.720 |
ENSPLAP00000029380 | ephx1 | ENSPLAP00000029380 | ENSPLAP00000010811 | Epoxide hydrolase 2, cytoplasmic. | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. | 0.695 |
ENSPLAP00000029380 | lipe | ENSPLAP00000029380 | ENSPLAP00000005850 | Epoxide hydrolase 2, cytoplasmic. | Lipase, hormone-sensitive b. | 0.564 |
ENSPLAP00000029380 | metap1d | ENSPLAP00000029380 | ENSPLAP00000027023 | Epoxide hydrolase 2, cytoplasmic. | Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). | 0.485 |
ENSPLAP00000029380 | nceh1 | ENSPLAP00000029380 | ENSPLAP00000006629 | Epoxide hydrolase 2, cytoplasmic. | Neutral cholesterol ester hydrolase 1a. | 0.584 |