STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMEP00000000053Purinergic receptor P2X, ligand-gated ion channel, 1. (322 aa)    
Predicted Functional Partners:
chek2
Checkpoint kinase 2.
   
 0.870
chek1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
 0.856
p2rx2
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.806
p2rx5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.795
LOC106932670
Purinergic receptor P2X, ligand-gated ion channel, 3b.
  
  
0.780
p2rx3
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
  
  
0.767
ccne1
Cyclin E1; Belongs to the cyclin family.
   
 0.734
ccne2
Cyclin E2; Belongs to the cyclin family.
   
 0.734
plk2
Serine/threonine-protein kinase PLK.
   
 0.715
plk4
Polo-like kinase 4 (Drosophila).
   
 0.715
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.