Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMEP00000001015Ig-like domain-containing protein. (142 aa)    
Predicted Functional Partners:
LOC106919087
Sodium channel, voltage-gated, type IV, beta b.
     
  0.900
LOC106927629
Sodium channel, voltage-gated, type I, beta b.
     
  0.900
LOC106909648
Si:ch211-225p5.8.
     
  0.900
LOC106916028
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
  0.900
ENSPMEP00000022245
Ig-like domain-containing protein.
     
 
0.900
LOC106926949
Uncharacterized protein.
     
  0.900
LOC106909653
Sodium channel, voltage-gated, type I, beta a.
     
  0.900
LOC106922467
Sodium channel, voltage-gated, type IV, beta a.
     
  0.900
LOC106923625
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
  0.683
LOC106906228
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
  0.683
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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