Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC106922113Amino acid transporter. (536 aa)    
Predicted Functional Partners:
cldn19
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.658
srgap3
SLIT-ROBO Rho GTPase activating protein 3.
     
 0.602
LOC106931353
Musculoskeletal, embryonic nuclear protein 1b.
     
 0.563
blmh
Bleomycin hydrolase; Belongs to the peptidase C1 family.
     
 0.539
LOC106905749
Solute carrier family 7 member 5.
  
 
 0.522
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.511
LOC106907025
V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
 
 0.508
med19
Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.500
slc3a1
Solute carrier family 3 member 1.
  
 
 0.486
LOC106907024
Chloride channel protein.
     
 0.478
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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