STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abcc3ATP-binding cassette, sub-family C (CFTR/MRP), member 3. (1475 aa)    
Predicted Functional Partners:
suox
Sulfite oxidase.
   
 
  0.850
katnal2
Katanin p60 subunit A-like 2.
  
 0.709
gopc
Golgi-associated PDZ and coiled-coil motif containing.
   
 0.671
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.662
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
  0.649
ENSPMEP00000021397
Hydroxysteroid dehydrogenase like 2.
  
 0.604
ENSPMEP00000015565
NDK domain-containing protein.
  
 0.597
acacb
Acetyl-CoA carboxylase beta.
 
 0.592
acaca
Acetyl-CoA carboxylase alpha.
 
 0.592
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
  0.591
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.