Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSPMEP00000001239Protein kinase domain-containing protein. (374 aa)    
Predicted Functional Partners:
ENSPMEP00000023098
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.934
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.931
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.906
LOC106910213
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.878
vegfb
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.876
vegfa
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
    
 0.870
grb2
Growth factor receptor-bound protein 2b.
    
 0.823
shc2
SHC (Src homology 2 domain containing) transforming protein 2.
    
  0.806
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.797
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.777
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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