Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casp8ap2Uncharacterized protein. (1829 aa)    
Predicted Functional Partners:
ENSPMEP00000028131
LisH domain-containing protein.
   
 
 0.794
LOC106926427
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 
 0.725
LOC106924075
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 
 0.725
ubr7
Ubiquitin protein ligase E3 component n-recognin 7.
      
 0.712
dscc1
DNA replication and sister chromatid cohesion 1.
      
 0.711
wdr76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
      
 0.704
prim1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.695
gins2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
      
 0.687
pola1
DNA polymerase.
   
  
 0.681
sumo1
Small ubiquitin-related modifier.
    
  0.675
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.