| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atm | atr | ENSPMEP00000027939 | ENSPMEP00000027005 | Non-specific serine/threonine protein kinase. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.999 |
| atm | brca1 | ENSPMEP00000027939 | ENSPMEP00000033157 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.999 |
| atm | cdc25b | ENSPMEP00000027939 | ENSPMEP00000012929 | Non-specific serine/threonine protein kinase. | Rhodanese domain-containing protein. | 0.696 |
| atm | cdc45 | ENSPMEP00000027939 | ENSPMEP00000003076 | Non-specific serine/threonine protein kinase. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.580 |
| atm | chek1 | ENSPMEP00000027939 | ENSPMEP00000001319 | Non-specific serine/threonine protein kinase. | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | 0.998 |
| atm | chek2 | ENSPMEP00000027939 | ENSPMEP00000030705 | Non-specific serine/threonine protein kinase. | Checkpoint kinase 2. | 0.999 |
| atm | clspn | ENSPMEP00000027939 | ENSPMEP00000023451 | Non-specific serine/threonine protein kinase. | Uncharacterized protein. | 0.810 |
| atm | rad51 | ENSPMEP00000027939 | ENSPMEP00000027531 | Non-specific serine/threonine protein kinase. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.997 |
| atm | tp53 | ENSPMEP00000027939 | ENSPMEP00000001243 | Non-specific serine/threonine protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| atr | atm | ENSPMEP00000027005 | ENSPMEP00000027939 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Non-specific serine/threonine protein kinase. | 0.999 |
| atr | brca1 | ENSPMEP00000027005 | ENSPMEP00000033157 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.999 |
| atr | cdc25b | ENSPMEP00000027005 | ENSPMEP00000012929 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Rhodanese domain-containing protein. | 0.956 |
| atr | cdc45 | ENSPMEP00000027005 | ENSPMEP00000003076 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.947 |
| atr | chek1 | ENSPMEP00000027005 | ENSPMEP00000001319 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | 0.999 |
| atr | chek2 | ENSPMEP00000027005 | ENSPMEP00000030705 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Checkpoint kinase 2. | 0.998 |
| atr | clspn | ENSPMEP00000027005 | ENSPMEP00000023451 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Uncharacterized protein. | 0.976 |
| atr | mcm4 | ENSPMEP00000027005 | ENSPMEP00000034612 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA helicase; Belongs to the MCM family. | 0.959 |
| atr | rad51 | ENSPMEP00000027005 | ENSPMEP00000027531 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.982 |
| atr | tp53 | ENSPMEP00000027005 | ENSPMEP00000001243 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.999 |
| brca1 | atm | ENSPMEP00000033157 | ENSPMEP00000027939 | Uncharacterized protein. | Non-specific serine/threonine protein kinase. | 0.999 |
