Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
serpinf1SERPIN domain-containing protein; Belongs to the serpin family. (405 aa)    
Predicted Functional Partners:
LOC106909474
Low density lipoprotein receptor-related protein 5.
    
 0.918
lrp6
Low density lipoprotein receptor-related protein 6.
    
 0.918
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 0.815
LOC106934301
Interferon induced transmembrane protein 5.
    
 0.766
LOC106926205
Peptidylprolyl isomerase.
   
 
 0.758
LOC106933294
Uncharacterized protein.
  
 0.758
crtap
Cartilage associated protein.
     
 0.753
sec24d
SEC24 homolog D, COPII coat complex component.
     
 0.738
p3h1
Prolyl 3-hydroxylase 1.
     
 0.736
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
  
0.728
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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