Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gtf2ird1GTF2I repeat domain containing 1. (1001 aa)    
Predicted Functional Partners:
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.822
nsun5
NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.750
zmym2
Zinc finger, MYM-type 2.
    
 
 0.702
baz1b
Bromodomain adjacent to zinc finger domain, 1B.
      
 0.699
tp53bp1
Tumor protein p53 binding protein, 1.
    
   0.697
fkbp6
Peptidylprolyl isomerase.
      
 0.687
rfc2
Replication factor C (activator 1) 2.
      
 0.686
wdr53
WD repeat domain 53.
      
 0.683
LOC106918874
Uncharacterized protein.
    
 
 0.671
tmem132e
Transmembrane protein 132E.
      
 0.660
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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