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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMEP00000001432Calponin-homology (CH) domain-containing protein. (90 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.918
LOC106933042
Cell division cycle 42.
   
 0.801
CDC42
Cell division cycle 42.
   
 0.801
LOC106917666
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.756
LOC106915552
Uncharacterized protein.
    
 0.756
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.756
ZAP70
Tyrosine-protein kinase.
   
 0.751
syk
Tyrosine-protein kinase.
   
 0.751
LOC106925948
Tyrosine-protein kinase.
   
 0.751
LOC106928254
Uncharacterized protein.
   
 0.728
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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