Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (562 aa)    
Predicted Functional Partners:
gpaa1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.999
pigk
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 0.999
pigt
Phosphatidylinositol glycan anchor biosynthesis, class T.
   
 0.999
pigu
Phosphatidylinositol glycan anchor biosynthesis, class U.
   
 0.999
ENSPMEP00000018614
PGRP domain-containing protein.
   
 0.966
pgap1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 0.956
pigg
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 0.933
pigf
Phosphatidylinositol glycan anchor biosynthesis, class F.
     
 0.929
ovca2
OVCA2 serine hydrolase domain containing.
   
   0.807
pigv
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 
 0.709
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.