STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parp3Poly [ADP-ribose] polymerase. (522 aa)    
Predicted Functional Partners:
LOC106906082
Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
    
 0.974
LOC106931868
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.974
casp7
Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.974
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
  
 
0.973
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.965
LOC106925480
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.959
LOC106925477
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.953
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.949
parp2
Poly [ADP-ribose] polymerase.
  
 
0.933
LOC106925481
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.914
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.