parp3 protein (Poecilia mexicana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

parp3

Poly [ADP-ribose] polymerase. (522 aa)

Predicted Functional Partners:

parp1

0.967

CASP3

0.935

LOC106906082

0.935

casp9

0.935

LOC106931868

0.935

casp7

0.935

LOC106915224

0.929

LOC106931137

0.929

pcna

0.897

xrcc6

0.891

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	LOC106906082	ENSPMEP00000002663	ENSPMEP00000022459	Caspase 3; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
CASP3	casp9	ENSPMEP00000002663	ENSPMEP00000024852	Caspase 3; Belongs to the peptidase C14A family.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.990
CASP3	parp1	ENSPMEP00000002663	ENSPMEP00000011797	Caspase 3; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.985
CASP3	parp3	ENSPMEP00000002663	ENSPMEP00000001628	Caspase 3; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase.	0.935
CASP3	pcna	ENSPMEP00000002663	ENSPMEP00000006790	Caspase 3; Belongs to the peptidase C14A family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.640
LOC106906082	CASP3	ENSPMEP00000022459	ENSPMEP00000002663	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.902
LOC106906082	casp9	ENSPMEP00000022459	ENSPMEP00000024852	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.990
LOC106906082	parp1	ENSPMEP00000022459	ENSPMEP00000011797	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.985
LOC106906082	parp3	ENSPMEP00000022459	ENSPMEP00000001628	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase.	0.935
LOC106906082	pcna	ENSPMEP00000022459	ENSPMEP00000006790	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.551
LOC106915224	LOC106931137	ENSPMEP00000002942	ENSPMEP00000017451	Poly (ADP-ribose) glycohydrolase, like.	Uncharacterized protein.	0.908
LOC106915224	parp1	ENSPMEP00000002942	ENSPMEP00000011797	Poly (ADP-ribose) glycohydrolase, like.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.977
LOC106915224	parp3	ENSPMEP00000002942	ENSPMEP00000001628	Poly (ADP-ribose) glycohydrolase, like.	Poly [ADP-ribose] polymerase.	0.929
LOC106915224	pcna	ENSPMEP00000002942	ENSPMEP00000006790	Poly (ADP-ribose) glycohydrolase, like.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.860
LOC106915224	xrcc6	ENSPMEP00000002942	ENSPMEP00000015893	Poly (ADP-ribose) glycohydrolase, like.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.479
LOC106931137	LOC106915224	ENSPMEP00000017451	ENSPMEP00000002942	Uncharacterized protein.	Poly (ADP-ribose) glycohydrolase, like.	0.908
LOC106931137	parp1	ENSPMEP00000017451	ENSPMEP00000011797	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.977
LOC106931137	parp3	ENSPMEP00000017451	ENSPMEP00000001628	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.929
LOC106931137	pcna	ENSPMEP00000017451	ENSPMEP00000006790	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.860
LOC106931137	xrcc6	ENSPMEP00000017451	ENSPMEP00000015893	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 6.	0.479