STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbr4Carbonyl reductase 4. (238 aa)    
Predicted Functional Partners:
hsd17b8
Hydroxysteroid (17-beta) dehydrogenase 8.
  
 
0.994
oxsm
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.981
fasn
Coiled-coil domain containing 57.
   
 0.928
mcat
Malonyl CoA:ACP acyltransferase (mitochondrial).
 
 0.917
HTD2
Hydroxyacyl-thioester dehydratase type 2.
  
 0.917
LOC106918839
Dehydrogenase/reductase (SDR family) member 4.
  
 
0.822
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 0.790
LOC106912214
Succinyl-CoA:glutarate-CoA transferase.
   
 0.770
LOC106925725
Carrier domain-containing protein.
   
 0.753
LOC106923956
Si:dkey-61p9.11.
   
 0.753
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.