Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbr4Carbonyl reductase 4. (238 aa)    
Predicted Functional Partners:
hsd17b8
Hydroxysteroid (17-beta) dehydrogenase 8.
  
 
0.999
oxsm
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.981
HTD2
Hydroxyacyl-thioester dehydratase type 2.
  
 0.946
fasn
Coiled-coil domain containing 57.
    
 0.939
LOC106933477
Septin 9a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
   0.760
LOC106917916
Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
   0.760
LOC106904178
Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
   0.760
LOC106918689
Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
   0.760
mecr
Mitochondrial trans-2-enoyl-CoA reductase.
  
 0.726
mcat
Malonyl CoA:ACP acyltransferase (mitochondrial).
 
 
 0.724
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.