Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC106914434Insulin-like growth factor binding protein 1a. (255 aa)    
Predicted Functional Partners:
igf1
Insulin-like growth factor 1.
    
 0.980
LOC106905258
Insulin-like growth factor 2b.
   
 0.849
ptges
Prostaglandin E synthase.
      
 0.689
corin
Corin, serine peptidase.
    
 
 0.668
igf2r
Insulin-like growth factor 2 receptor.
      
 0.660
LOC106918803
Alpha-2-HS-glycoprotein 2.
   
  
 0.643
htr2b
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled.
      
 0.625
prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
      
 0.623
fam20c
FAM20C golgi associated secretory pathway kinase a.
    
  0.550
LOC106928665
Fibronectin type-III domain-containing protein.
      
 0.549
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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