Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mazMYC associated zinc finger protein. (456 aa)    
Predicted Functional Partners:
rnf4
RING-type domain-containing protein.
    
 
 0.590
sez6l2
Seizure related 6 homolog (mouse)-like 2.
    
 
 0.571
LOC106907029
Protein yippee-like; Belongs to the yippee family.
    
 
 0.571
mysm1
Myb-like, SWIRM and MPN domains 1.
    
  0.570
ENSPMEP00000015565
NDK domain-containing protein.
    
 0.557
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
  0.548
ENSPMEP00000030751
Proline-rich transmembrane protein 2.
      
 0.533
LOC106906762
Uncharacterized protein.
      
 0.530
nisch
PX domain-containing protein.
      
 0.521
kctd13
Potassium channel tetramerization domain containing 13.
    
 
 0.518
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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