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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmncUncharacterized protein. (341 aa)    
Predicted Functional Partners:
IWS1
Interacts with SUPT6H, CTD assembly factor 1.
  
   
 0.601
LOC106903803
Forkhead box J1b.
      
 0.564
larp6
La ribonucleoprotein domain family, member 6a.
      
 0.562
ENSPMEP00000003839
Phosphatase, orphan 1.
      
 0.514
LOC106928596
Phosphatase, orphan 2.
      
 0.514
rfx4
Regulatory factor X, 4.
      
 0.502
topbp1
DNA topoisomerase II binding protein 1.
      
 0.499
ENSPMEP00000017144
HTH La-type RNA-binding domain-containing protein.
      
 0.489
LOC106923937
VPS9 domain-containing protein.
  
     0.417
rfx2
Regulatory factor X, 2 (influences HLA class II expression).
      
 0.400
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.