| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| UBE3A | neurl4 | ENSPMEP00000001968 | ENSPMEP00000001104 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Neuralized E3 ubiquitin protein ligase 4. | 0.953 |
| UBE3A | psmc1 | ENSPMEP00000001968 | ENSPMEP00000033798 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | 0.981 |
| UBE3A | psmc3 | ENSPMEP00000001968 | ENSPMEP00000010173 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. | 0.958 |
| UBE3A | psmc4 | ENSPMEP00000001968 | ENSPMEP00000019836 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. | 0.965 |
| UBE3A | psmd12 | ENSPMEP00000001968 | ENSPMEP00000030666 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Proteasome 26S subunit, non-ATPase 12. | 0.953 |
| UBE3A | psmd14 | ENSPMEP00000001968 | ENSPMEP00000029990 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Proteasome 26S subunit, non-ATPase 14. | 0.976 |
| UBE3A | psmd2 | ENSPMEP00000001968 | ENSPMEP00000015368 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.965 |
| UBE3A | tat | ENSPMEP00000001968 | ENSPMEP00000032758 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.974 |
| UBE3A | tp53 | ENSPMEP00000001968 | ENSPMEP00000001243 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.991 |
| UBE3A | uchl5 | ENSPMEP00000001968 | ENSPMEP00000010212 | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | Ubiquitin carboxyl-terminal hydrolase. | 0.970 |
| neurl4 | UBE3A | ENSPMEP00000001104 | ENSPMEP00000001968 | Neuralized E3 ubiquitin protein ligase 4. | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | 0.953 |
| neurl4 | tp53 | ENSPMEP00000001104 | ENSPMEP00000001243 | Neuralized E3 ubiquitin protein ligase 4. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.781 |
| psmc1 | UBE3A | ENSPMEP00000033798 | ENSPMEP00000001968 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. | 0.981 |
| psmc1 | psmc3 | ENSPMEP00000033798 | ENSPMEP00000010173 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. | 0.999 |
| psmc1 | psmc4 | ENSPMEP00000033798 | ENSPMEP00000019836 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. | 0.999 |
| psmc1 | psmd12 | ENSPMEP00000033798 | ENSPMEP00000030666 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 12. | 0.999 |
| psmc1 | psmd14 | ENSPMEP00000033798 | ENSPMEP00000029990 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Proteasome 26S subunit, non-ATPase 14. | 0.999 |
| psmc1 | psmd2 | ENSPMEP00000033798 | ENSPMEP00000015368 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
| psmc1 | tp53 | ENSPMEP00000033798 | ENSPMEP00000001243 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.688 |
| psmc1 | uchl5 | ENSPMEP00000033798 | ENSPMEP00000010212 | Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. | Ubiquitin carboxyl-terminal hydrolase. | 0.992 |
