STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr2-2TIR domain-containing protein. (816 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.989
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.981
tollip
Toll interacting protein.
    
 0.971
LOC106920307
Toll-like receptor 1.
  
  
0.962
tlr2
Toll-like receptor 2; Belongs to the Toll-like receptor family.
  
  
 
0.959
LOC106928254
Uncharacterized protein.
   
 0.923
LOC106925836
Uncharacterized protein.
   
 0.923
LOC106925839
Uncharacterized protein.
   
 0.923
LOC106925835
Uncharacterized protein.
   
 0.922
LOC106925837
Uncharacterized protein.
   
 0.918
Your Current Organism:
Poecilia mexicana
NCBI taxonomy Id: 48701
Other names: shortfin molly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.