sost protein (Poecilia mexicana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

sost

Sclerostin. (230 aa)

Predicted Functional Partners:

LOC106909474

0.992

lrp6

0.988

LOC106920878

0.779

ENSPMEP00000012202

0.701

LOC106915127

0.688

mapk10

0.688

mapk8

0.688

mapk1

0.687

mapk7

0.687

LOC106906981

0.687

Your Current Organism:

Poecilia mexicana

NCBI taxonomy Id: 48701
Other names: shortfin molly

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPMEP00000012202	LOC106906981	ENSPMEP00000012202	ENSPMEP00000034774	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.933
ENSPMEP00000012202	LOC106915127	ENSPMEP00000012202	ENSPMEP00000004458	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase.	0.900
ENSPMEP00000012202	LOC106920878	ENSPMEP00000012202	ENSPMEP00000007292	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase.	0.899
ENSPMEP00000012202	mapk1	ENSPMEP00000012202	ENSPMEP00000010486	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.933
ENSPMEP00000012202	mapk10	ENSPMEP00000012202	ENSPMEP00000016906	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase.	0.900
ENSPMEP00000012202	mapk7	ENSPMEP00000012202	ENSPMEP00000029958	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.780
ENSPMEP00000012202	mapk8	ENSPMEP00000012202	ENSPMEP00000022501	Protein tyrosine phosphatase non-receptor type 5.	Mitogen-activated protein kinase.	0.892
ENSPMEP00000012202	sost	ENSPMEP00000012202	ENSPMEP00000006748	Protein tyrosine phosphatase non-receptor type 5.	Sclerostin.	0.701
LOC106906981	ENSPMEP00000012202	ENSPMEP00000034774	ENSPMEP00000012202	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein tyrosine phosphatase non-receptor type 5.	0.933
LOC106906981	LOC106915127	ENSPMEP00000034774	ENSPMEP00000004458	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.555
LOC106906981	LOC106920878	ENSPMEP00000034774	ENSPMEP00000007292	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.593
LOC106906981	mapk1	ENSPMEP00000034774	ENSPMEP00000010486	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.921
LOC106906981	mapk10	ENSPMEP00000034774	ENSPMEP00000016906	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.551
LOC106906981	mapk8	ENSPMEP00000034774	ENSPMEP00000022501	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.555
LOC106906981	sost	ENSPMEP00000034774	ENSPMEP00000006748	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Sclerostin.	0.687
LOC106909474	lrp6	ENSPMEP00000012996	ENSPMEP00000024213	Low density lipoprotein receptor-related protein 5.	Low density lipoprotein receptor-related protein 6.	0.944
LOC106909474	sost	ENSPMEP00000012996	ENSPMEP00000006748	Low density lipoprotein receptor-related protein 5.	Sclerostin.	0.992
LOC106915127	ENSPMEP00000012202	ENSPMEP00000004458	ENSPMEP00000012202	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 5.	0.900
LOC106915127	LOC106906981	ENSPMEP00000004458	ENSPMEP00000034774	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.555
LOC106915127	LOC106920878	ENSPMEP00000004458	ENSPMEP00000007292	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.985