STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ocin01_07516Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (441 aa)    
Predicted Functional Partners:
Ocin01_07009
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
    
 0.914
Ocin01_04731
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
   
  
 0.901
Ocin01_14273
Putative ATP-dependent RNA helicase DDX56.
  
  
 0.788
Ocin01_08269
Putative ATP-dependent RNA helicase DDX56.
  
  
 0.788
Ocin01_00541
GMP synthase [glutamine-hydrolyzing].
  
 
 0.787
Ocin01_09580
tRNA (Adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6.
   
  
 0.786
Ocin01_15592
Adenylyltransferase and sulfurtransferase MOCS3.
  
 
 0.779
Ocin01_11211
Adenylyltransferase and sulfurtransferase MOCS3.
  
 
 0.779
Ocin01_09865
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
   
 0.757
Ocin01_03528
Phosphoglucomutase-2.
   
 0.757
Your Current Organism:
Orchesella cincta
NCBI taxonomy Id: 48709
Other names: O. cincta
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