STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureC-2Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)    
Predicted Functional Partners:
OBI51677.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.763
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.624
OBI40404.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.582
OBI50139.1
WYL domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.580
OBI46744.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.577
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
 
 
 
 0.536
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
 
 
 
 0.528
OBI40300.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.491
OBI43181.1
Pyridoxamine 5'-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.452
OBI40236.1
Flavin-nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.452
Your Current Organism:
Mycobacterium kyorinense
NCBI taxonomy Id: 487514
Other names: DSM 45166, JCM 15038, M. kyorinense, Mycobacterium kyorinense Okazaki et al. 2009, strain KUM 060204
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.