STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFM44674.1Hypothetical protein. (248 aa)    
Predicted Functional Partners:
SFM44694.1
Hypothetical protein.
 
     0.738
cdhB
acetyl-CoA decarbonylase/synthase epsilon subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation.
 
     0.686
cdhA
acetyl-CoA decarbonylase/synthase alpha subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
     0.683
SFM44728.1
Uncharacterized protein.
       0.664
SFM55742.1
Formylmethanofuran dehydrogenase, subunit G.
 
     0.663
dut
dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
  0.657
SFM44709.1
Amino-acid N-acetyltransferase.
       0.645
cdhD
acetyl-CoA decarbonylase/synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex.
 
     0.620
SFM55706.1
Formylmethanofuran dehydrogenase, subunit D.
 
     0.561
SFM16290.1
4-hydroxybenzoate synthetase (chorismate-pyruvate lyase).
  
     0.560
Your Current Organism:
Methanolobus profundi
NCBI taxonomy Id: 487685
Other names: DSM 21213, M. profundi, Methanolobus profundi Mochimaru et al. 2009, Methanolobus sp. MobM, NBRC 104158, strain Mob M, strain MobM
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