STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFM60697.1Methanol-specific methylcobalamin: coenzyme M methyltransferase. (336 aa)    
Predicted Functional Partners:
SFM71055.1
Trimethylamine:corrinoid methyltransferase; Manually curated; Belongs to the trimethylamine methyltransferase family.
  
  
 0.891
SFM14231.1
B12 binding domain-containing protein.
 
 
 0.847
SFM58435.1
Methyl-coenzyme M reductase, beta subunit.
  
  
 0.836
SFM58348.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
  
 0.833
SFM58366.1
Methyl-coenzyme M reductase, gamma subunit.
  
  
 0.830
SFM68803.1
Methyl coenzyme M reductase system, component A2.
 
 
 0.812
SFM58390.1
Methyl-coenzyme M reductase subunit C.
  
  
  0.809
SFM28244.1
Methanol:corrinoid methyltransferase.
  
  
 0.758
SFM60647.1
Methanol:corrinoid methyltransferase.
  
  
 0.752
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.739
Your Current Organism:
Methanolobus profundi
NCBI taxonomy Id: 487685
Other names: DSM 21213, M. profundi, Methanolobus profundi Mochimaru et al. 2009, Methanolobus sp. MobM, NBRC 104158, strain Mob M, strain MobM
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