STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG40827.1TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: gfo:GFO_2076 isochorismate synthase. (347 aa)    
Predicted Functional Partners:
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
 0.961
EEG40821.1
KEGG: fps:FP1601 O-succinylbenzoate--CoA ligase.
 
   
 0.892
EEG40823.1
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: fjo:Fjoh_2788 mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
 
   
 0.887
EEG40828.1
PFAM: thioesterase superfamily protein; KEGG: gfo:GFO_2077 thioesterase superfamily protein.
 
  
 0.871
EEG41969.1
PFAM: Chorismate mutase; DAHP synthetase I/KDSA; KEGG: gfo:GFO_0343 bifunctional AroA(G) protein.
 
 
 0.866
EEG41137.1
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: fjo:Fjoh_4892 glutamine amidotransferase of anthranilate synthase.
  
 
  0.863
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.853
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.852
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
  
  0.787
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.728
Your Current Organism:
Flavobacteria bacterium MS0242A
NCBI taxonomy Id: 487796
Other names: F. bacterium MS024-2A, Flavobacteria bacterium MS024-2A
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