node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEG40712.1 | EEG41589.1 | Flav2ADRAFT_0012 | Flav2ADRAFT_0893 | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: fjo:Fjoh_0354 dTDP-glucose 4,6-dehydratase. | KEGG: fjo:Fjoh_0875 NAD-dependent epimerase/dehydratase. | 0.404 |
EEG40712.1 | EEG41590.1 | Flav2ADRAFT_0012 | Flav2ADRAFT_0894 | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: fjo:Fjoh_0354 dTDP-glucose 4,6-dehydratase. | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | 0.614 |
EEG40712.1 | ribB | Flav2ADRAFT_0012 | Flav2ADRAFT_1539 | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: fjo:Fjoh_0354 dTDP-glucose 4,6-dehydratase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.445 |
EEG41589.1 | EEG40712.1 | Flav2ADRAFT_0893 | Flav2ADRAFT_0012 | KEGG: fjo:Fjoh_0875 NAD-dependent epimerase/dehydratase. | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: fjo:Fjoh_0354 dTDP-glucose 4,6-dehydratase. | 0.404 |
EEG41589.1 | EEG41590.1 | Flav2ADRAFT_0893 | Flav2ADRAFT_0894 | KEGG: fjo:Fjoh_0875 NAD-dependent epimerase/dehydratase. | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | 0.557 |
EEG41589.1 | ribB | Flav2ADRAFT_0893 | Flav2ADRAFT_1539 | KEGG: fjo:Fjoh_0875 NAD-dependent epimerase/dehydratase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.450 |
EEG41590.1 | EEG40712.1 | Flav2ADRAFT_0894 | Flav2ADRAFT_0012 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: fjo:Fjoh_0354 dTDP-glucose 4,6-dehydratase. | 0.614 |
EEG41590.1 | EEG41589.1 | Flav2ADRAFT_0894 | Flav2ADRAFT_0893 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | KEGG: fjo:Fjoh_0875 NAD-dependent epimerase/dehydratase. | 0.557 |
EEG41590.1 | EEG42199.1 | Flav2ADRAFT_0894 | Flav2ADRAFT_1507 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.562 |
EEG41590.1 | adk | Flav2ADRAFT_0894 | Flav2ADRAFT_1371 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.695 |
EEG41590.1 | atpH | Flav2ADRAFT_0894 | Flav2ADRAFT_0768 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.585 |
EEG41590.1 | guaA | Flav2ADRAFT_0894 | Flav2ADRAFT_0497 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.855 |
EEG41590.1 | purA | Flav2ADRAFT_0894 | Flav2ADRAFT_0539 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.585 |
EEG41590.1 | pyrD | Flav2ADRAFT_0894 | Flav2ADRAFT_1602 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.588 |
EEG41590.1 | ribB | Flav2ADRAFT_0894 | Flav2ADRAFT_1539 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.623 |
EEG41590.1 | surE | Flav2ADRAFT_0894 | Flav2ADRAFT_0572 | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.615 |
EEG42199.1 | EEG41590.1 | Flav2ADRAFT_1507 | Flav2ADRAFT_0894 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: gfo:GFO_3116 protein containing CBS domains. | 0.562 |
EEG42199.1 | adk | Flav2ADRAFT_1507 | Flav2ADRAFT_1371 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.843 |
EEG42199.1 | guaA | Flav2ADRAFT_1507 | Flav2ADRAFT_0497 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.894 |
EEG42199.1 | purA | Flav2ADRAFT_1507 | Flav2ADRAFT_0539 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.757 |