| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKK66806.1 | AKK67030.1 | FD63_04590 | FD63_05805 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| AKK66806.1 | AKK68678.1 | FD63_04590 | FD63_14975 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
| AKK66806.1 | AKK68766.1 | FD63_04590 | FD63_15440 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| AKK66806.1 | gltA | FD63_04590 | FD63_03295 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.925 |
| AKK66806.1 | prpC | FD63_04590 | FD63_04600 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
| AKK66806.1 | sucC | FD63_04590 | FD63_14525 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.851 |
| AKK66806.1 | sucD | FD63_04590 | FD63_14520 | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.623 |
| AKK67030.1 | AKK66806.1 | FD63_05805 | FD63_04590 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| AKK67030.1 | AKK68678.1 | FD63_05805 | FD63_14975 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| AKK67030.1 | AKK68766.1 | FD63_05805 | FD63_15440 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
| AKK67030.1 | gltA | FD63_05805 | FD63_03295 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.669 |
| AKK67030.1 | icmF | FD63_05805 | FD63_05995 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.715 |
| AKK67030.1 | prpC | FD63_05805 | FD63_04600 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| AKK67030.1 | sucC | FD63_05805 | FD63_14525 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.699 |
| AKK67030.1 | sucD | FD63_05805 | FD63_14520 | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.467 |
| AKK68014.1 | AKK68678.1 | FD63_11305 | FD63_14975 | Polyhydroxyalkanoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.488 |
| AKK68677.1 | AKK68678.1 | FD63_14970 | FD63_14975 | Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
| AKK68678.1 | AKK66806.1 | FD63_14975 | FD63_04590 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.443 |
| AKK68678.1 | AKK67030.1 | FD63_14975 | FD63_05805 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| AKK68678.1 | AKK68014.1 | FD63_14975 | FD63_11305 | acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Polyhydroxyalkanoic acid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.488 |