| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKK66296.1 | AKK67554.1 | FD63_01695 | FD63_08715 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| AKK66296.1 | AKK68410.1 | FD63_01695 | FD63_13410 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| AKK66296.1 | AKK68567.1 | FD63_01695 | FD63_14345 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
| AKK66296.1 | AKK68990.1 | FD63_01695 | FD63_16670 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| AKK66296.1 | AKK68991.1 | FD63_01695 | FD63_16675 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AKK66296.1 | ahcY | FD63_01695 | FD63_15910 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.800 |
| AKK66296.1 | glyA | FD63_01695 | FD63_16170 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
| AKK66296.1 | metE | FD63_01695 | FD63_18620 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.834 |
| AKK66296.1 | metH | FD63_01695 | FD63_08710 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.810 |
| AKK67554.1 | AKK66296.1 | FD63_08715 | FD63_01695 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| AKK67554.1 | AKK68410.1 | FD63_08715 | FD63_13410 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
| AKK67554.1 | AKK68567.1 | FD63_08715 | FD63_14345 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.918 |
| AKK67554.1 | AKK68990.1 | FD63_08715 | FD63_16670 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
| AKK67554.1 | AKK68991.1 | FD63_08715 | FD63_16675 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
| AKK67554.1 | ahcY | FD63_08715 | FD63_15910 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.930 |
| AKK67554.1 | glyA | FD63_08715 | FD63_16170 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| AKK67554.1 | metE | FD63_08715 | FD63_18620 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.965 |
| AKK67554.1 | metH | FD63_08715 | FD63_08710 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| AKK68410.1 | AKK66296.1 | FD63_13410 | FD63_01695 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| AKK68410.1 | AKK67554.1 | FD63_13410 | FD63_08715 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |