| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKK69204.1 | AKK69205.1 | FD63_17850 | FD63_17855 | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
| AKK69204.1 | bfr-2 | FD63_17850 | FD63_17845 | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.945 |
| AKK69205.1 | AKK69204.1 | FD63_17855 | FD63_17850 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.684 |
| AKK69205.1 | apaH | FD63_17855 | FD63_03435 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.543 |
| AKK69205.1 | bfr-2 | FD63_17855 | FD63_17845 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | 0.539 |
| AKK69205.1 | birA | FD63_17855 | FD63_18570 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.587 |
| AKK69205.1 | dapF | FD63_17855 | FD63_03005 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.902 |
| AKK69205.1 | glyQ | FD63_17855 | FD63_19530 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glycyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.531 |
| AKK69205.1 | hfq | FD63_17855 | FD63_10925 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.627 |
| AKK69205.1 | nnrD | FD63_17855 | FD63_08125 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.718 |
| AKK69205.1 | rho | FD63_17855 | FD63_02325 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.531 |
| AKK69205.1 | rnr | FD63_17855 | FD63_12105 | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.604 |
| apaH | AKK69205.1 | FD63_03435 | FD63_17855 | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
| apaH | rnr | FD63_03435 | FD63_12105 | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.473 |
| bfr-2 | AKK69204.1 | FD63_17845 | FD63_17850 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.945 |
| bfr-2 | AKK69205.1 | FD63_17845 | FD63_17855 | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.539 |
| birA | AKK69205.1 | FD63_18570 | FD63_17855 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | RNA pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.587 |
| birA | dapF | FD63_18570 | FD63_03005 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.618 |
| birA | hfq | FD63_18570 | FD63_10925 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.585 |
| birA | nnrD | FD63_18570 | FD63_08125 | Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.443 |
