node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDW51624.1 | SDW51675.1 | SAMN04487960_10314 | SAMN04487960_10315 | Isoquinoline 1-oxidoreductase, alpha subunit. | Isoquinoline 1-oxidoreductase, beta subunit. | 0.999 |
SDW51624.1 | SDW51711.1 | SAMN04487960_10314 | SAMN04487960_10316 | Isoquinoline 1-oxidoreductase, alpha subunit. | Xanthine dehydrogenase accessory factor. | 0.949 |
SDW51624.1 | SDX11187.1 | SAMN04487960_10314 | SAMN04487960_106153 | Isoquinoline 1-oxidoreductase, alpha subunit. | Molybdenum cofactor cytidylyltransferase. | 0.898 |
SDW51624.1 | mtnB | SAMN04487960_10314 | SAMN04487960_10317 | Isoquinoline 1-oxidoreductase, alpha subunit. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.422 |
SDW51675.1 | SDW51624.1 | SAMN04487960_10315 | SAMN04487960_10314 | Isoquinoline 1-oxidoreductase, beta subunit. | Isoquinoline 1-oxidoreductase, alpha subunit. | 0.999 |
SDW51675.1 | SDW51711.1 | SAMN04487960_10315 | SAMN04487960_10316 | Isoquinoline 1-oxidoreductase, beta subunit. | Xanthine dehydrogenase accessory factor. | 0.955 |
SDW51675.1 | SDX11187.1 | SAMN04487960_10315 | SAMN04487960_106153 | Isoquinoline 1-oxidoreductase, beta subunit. | Molybdenum cofactor cytidylyltransferase. | 0.872 |
SDW51711.1 | SDW51624.1 | SAMN04487960_10316 | SAMN04487960_10314 | Xanthine dehydrogenase accessory factor. | Isoquinoline 1-oxidoreductase, alpha subunit. | 0.949 |
SDW51711.1 | SDW51675.1 | SAMN04487960_10316 | SAMN04487960_10315 | Xanthine dehydrogenase accessory factor. | Isoquinoline 1-oxidoreductase, beta subunit. | 0.955 |
SDW51711.1 | SDW51868.1 | SAMN04487960_10316 | SAMN04487960_10320 | Xanthine dehydrogenase accessory factor. | Protein of unknown function. | 0.567 |
SDW51711.1 | SDW94927.1 | SAMN04487960_10316 | SAMN04487960_105125 | Xanthine dehydrogenase accessory factor. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.615 |
SDW51711.1 | SDX10299.1 | SAMN04487960_10316 | SAMN04487960_106125 | Xanthine dehydrogenase accessory factor. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. | 0.437 |
SDW51711.1 | SDX11187.1 | SAMN04487960_10316 | SAMN04487960_106153 | Xanthine dehydrogenase accessory factor. | Molybdenum cofactor cytidylyltransferase. | 0.945 |
SDW51711.1 | mobA | SAMN04487960_10316 | SAMN04487960_105128 | Xanthine dehydrogenase accessory factor. | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. | 0.485 |
SDW51711.1 | mtnB | SAMN04487960_10316 | SAMN04487960_10317 | Xanthine dehydrogenase accessory factor. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.608 |
SDW51711.1 | mtnC | SAMN04487960_10316 | SAMN04487960_10319 | Xanthine dehydrogenase accessory factor. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.608 |
SDW51711.1 | mtnD | SAMN04487960_10316 | SAMN04487960_10318 | Xanthine dehydrogenase accessory factor. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.608 |
SDW51868.1 | SDW51711.1 | SAMN04487960_10320 | SAMN04487960_10316 | Protein of unknown function. | Xanthine dehydrogenase accessory factor. | 0.567 |
SDW51868.1 | mtnB | SAMN04487960_10320 | SAMN04487960_10317 | Protein of unknown function. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.722 |
SDW51868.1 | mtnC | SAMN04487960_10320 | SAMN04487960_10319 | Protein of unknown function. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.722 |